BDBM50295891 (Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one::CHEMBL561523

SMILES COc1cc(\C=C2/SC(=S)N(C2=O)c2cccc(c2)C(F)(F)F)cc(OC)c1O

InChI Key InChIKey=MASLKHTWMHYHNX-NVNXTCNLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295891   

TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295891((Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-2-thiox...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed