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BDBM50295936 7-Chloro-3-[(4-phenylpiperazin-1-yl)methyl]-1Hpyrrolo[2,3-c]pyridine::CHEMBL559868

SMILES: Clc1nccc2c(CN3CCN(CC3)c3ccccc3)c[nH]c12

InChI Key: InChIKey=CIQQYYDWFNUHDM-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295936   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50295936
PNG
(7-Chloro-3-[(4-phenylpiperazin-1-yl)methyl]-1Hpyrr...)
Show SMILES Clc1nccc2c(CN3CCN(CC3)c3ccccc3)c[nH]c12
Show InChI InChI=1S/C18H19ClN4/c19-18-17-16(6-7-20-18)14(12-21-17)13-22-8-10-23(11-9-22)15-4-2-1-3-5-15/h1-7,12,21H,8-11,13H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.60E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander-Universit£t

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23390 from human cloned dopamine D2 long receptor expressed in CHO cells


Bioorg Med Chem 17: 4448-58 (2009)


Article DOI: 10.1016/j.bmc.2009.05.015
BindingDB Entry DOI: 10.7270/Q2P55NKX
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50295936
PNG
(7-Chloro-3-[(4-phenylpiperazin-1-yl)methyl]-1Hpyrr...)
Show SMILES Clc1nccc2c(CN3CCN(CC3)c3ccccc3)c[nH]c12
Show InChI InChI=1S/C18H19ClN4/c19-18-17-16(6-7-20-18)14(12-21-17)13-22-8-10-23(11-9-22)15-4-2-1-3-5-15/h1-7,12,21H,8-11,13H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.90E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander-Universit£t

Curated by ChEMBL


Assay Description
Displacement of [3H]spiroperidol from human cloned dopamine D2 short receptor expressed in CHO cells


Bioorg Med Chem 17: 4448-58 (2009)


Article DOI: 10.1016/j.bmc.2009.05.015
BindingDB Entry DOI: 10.7270/Q2P55NKX
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50295936
PNG
(7-Chloro-3-[(4-phenylpiperazin-1-yl)methyl]-1Hpyrr...)
Show SMILES Clc1nccc2c(CN3CCN(CC3)c3ccccc3)c[nH]c12
Show InChI InChI=1S/C18H19ClN4/c19-18-17-16(6-7-20-18)14(12-21-17)13-22-8-10-23(11-9-22)15-4-2-1-3-5-15/h1-7,12,21H,8-11,13H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
6.10E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander-Universit£t

Curated by ChEMBL


Assay Description
Displacement of [3H]spiroperidol from human cloned dopamine D3 receptor expressed in CHO cells


Bioorg Med Chem 17: 4448-58 (2009)


Article DOI: 10.1016/j.bmc.2009.05.015
BindingDB Entry DOI: 10.7270/Q2P55NKX
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50295936
PNG
(7-Chloro-3-[(4-phenylpiperazin-1-yl)methyl]-1Hpyrr...)
Show SMILES Clc1nccc2c(CN3CCN(CC3)c3ccccc3)c[nH]c12
Show InChI InChI=1S/C18H19ClN4/c19-18-17-16(6-7-20-18)14(12-21-17)13-22-8-10-23(11-9-22)15-4-2-1-3-5-15/h1-7,12,21H,8-11,13H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
6.80E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander-Universit£t

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23390 from bovine dopamine D1 receptor


Bioorg Med Chem 17: 4448-58 (2009)


Article DOI: 10.1016/j.bmc.2009.05.015
BindingDB Entry DOI: 10.7270/Q2P55NKX
More data for this
Ligand-Target Pair