BDBM50296848 2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid::CHEMBL563949

SMILES: Cc1c(CC(O)=O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(F)c1

InChI Key: InChIKey=HLSYGDSWXJGENX-UHFFFAOYSA-N

Data: 3 KI  18 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50296848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 receptor (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin D2 receptor 2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin D2 receptor 2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin D2 receptor 2 (Mouse)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
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Cholecystokinin receptor type A (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin D2 receptor 2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin F2-alpha receptor (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP3 subtype (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Mouse)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Human)	BDBM50296848 (2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...) Show SMILES Show InChI	GoogleScholar	UniChem		31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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