BindingDB logo
myBDB logout

BDBM50297003 CHEMBL558062::N-(1-ethyl-4,6-dimethylindolin-7-yl)pivalamide

SMILES: CCN1CCc2c1c(NC(=O)C(C)(C)C)c(C)cc2C

InChI Key: InChIKey=LJSMVWQTCAREKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)
BDBM50297003
PNG
(CHEMBL558062 | N-(1-ethyl-4,6-dimethylindolin-7-yl...)
Show SMILES CCN1CCc2c1c(NC(=O)C(C)(C)C)c(C)cc2C
Show InChI InChI=1S/C17H26N2O/c1-7-19-9-8-13-11(2)10-12(3)14(15(13)19)18-16(20)17(4,5)6/h10H,7-9H2,1-6H3,(H,18,20)
PDB

Reactome pathway
KEGG

UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Kyoto Pharmaceutical Industries

Curated by ChEMBL


Assay Description
Inhibition of ACAT in Japanese White rabbit liver microsomes


Bioorg Med Chem 17: 6020-31 (2009)


Article DOI: 10.1016/j.bmc.2009.06.047
BindingDB Entry DOI: 10.7270/Q2222TTC
More data for this
Ligand-Target Pair