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BDBM50297980 3-((1R)-1-(2-chloro-4-((3-hydroxypyrrolidin-1-yl)methyl)phenyl)ethoxy)-5-(imidazo[1,2-a]pyridin-3-yl)thiophene-2-carboxamide::CHEMBL562735
SMILES: C[C@@H](Oc1cc(sc1C(N)=O)-c1cnc2ccccn12)c1ccc(CN2CCC(O)C2)cc1Cl
InChI Key: InChIKey=KSZQDCYDVPKHGA-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase PLK1 (Human) | BDBM50297980![]() (3-((1R)-1-(2-chloro-4-((3-hydroxypyrrolidin-1-yl)m...) | GoogleScholar | UniChem | n/a | n/a | n/a | n/a | 2.27E+5 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK1 (Human) | BDBM50297980![]() (3-((1R)-1-(2-chloro-4-((3-hydroxypyrrolidin-1-yl)m...) | GoogleScholar | UniChem | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||