BDBM50299299 CHEMBL575342::methyl 4-(2-hydroxy-5-methoxybenzylideneamino)benzoate

SMILES COC(=O)c1ccc(cc1)\N=C\c1cc(OC)ccc1O

InChI Key InChIKey=LHTZWZAZKLGYNX-LICLKQGHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299299   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Enscm-Umii-Cnrs 5635

Curated by ChEMBL
LigandPNGBDBM50299299(CHEMBL575342 | methyl 4-(2-hydroxy-5-methoxybenzyl...)
Affinity DataKi:  5.33E+3nMAssay Description:Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Enscm/Umii/Umr-Cnrs 5635

Curated by ChEMBL
LigandPNGBDBM50299299(CHEMBL575342 | methyl 4-(2-hydroxy-5-methoxybenzyl...)
Affinity DataKi:  7.45E+3nMAssay Description:Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Enscm-Umii-Cnrs 5635

Curated by ChEMBL
LigandPNGBDBM50299299(CHEMBL575342 | methyl 4-(2-hydroxy-5-methoxybenzyl...)
Affinity DataKi:  1.13E+4nMAssay Description:Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed