BDBM50299586 (S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazine-1-carboxamido)phenyl dimethylcarbamate::CHEMBL570116

SMILES: C[C@H]1CN(CCN1C(=O)Nc1cccc(OC(=O)N(C)C)c1)c1ncnc2[nH]cc(C)c12

InChI Key: InChIKey=MVPARBNSRQJBEM-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50299586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 1 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 1 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 1 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 1/2 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 1 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Human)	BDBM50299586 ((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair