BDBM50303698 CHEMBL567274::Thiophene-2-sulfonic Acid [(E)-3-(1-Naphthalen-2-ylmethyl-1H-indol-7-yl)acryloyl]amide

SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2ccn(Cc3ccc4ccccc4c3)c12

InChI Key InChIKey=BEQMJPPFUNGRON-OUKQBFOZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303698   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303698(CHEMBL567274 | Thiophene-2-sulfonic Acid [(E)-3-(1...)
Affinity DataIC50:  378nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303698(CHEMBL567274 | Thiophene-2-sulfonic Acid [(E)-3-(1...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP level after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed