BDBM50303698 CHEMBL567274::Thiophene-2-sulfonic Acid [(E)-3-(1-Naphthalen-2-ylmethyl-1H-indol-7-yl)acryloyl]amide
SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2ccn(Cc3ccc4ccccc4c3)c12
InChI Key InChIKey=BEQMJPPFUNGRON-OUKQBFOZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50303698
Affinity DataIC50: 378nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP level after 10 mins by EIAMore data for this Ligand-Target Pair