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BDBM50305902 (S)-methyl 2-(2-(4-chlorophenyl)-3-methylbutanamido)thiazole-5-carboxylate::CHEMBL594505

SMILES: COC(=O)c1cnc(NC(=O)[C@@H](C(C)C)c2ccc(Cl)cc2)s1

InChI Key: InChIKey=FMHTWEXHAZHRHI-UGPWUYPHNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305902   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))
BDBM50305902
PNG
((S)-methyl 2-(2-(4-chlorophenyl)-3-methylbutanamid...)
Show SMILES COC(=O)c1cnc(NC(=O)[C@@H](C(C)C)c2ccc(Cl)cc2)s1
Show InChI InChI=1/C16H17ClN2O3S/c1-9(2)13(10-4-6-11(17)7-5-10)14(20)19-16-18-8-12(23-16)15(21)22-3/h4-9,13H,1-3H3,(H,18,19,20)/t13-/s2
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Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 20: 493-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.112
BindingDB Entry DOI: 10.7270/Q21V5F2Q
More data for this
Ligand-Target Pair