BDBM50305987 5,6-bis(4-chlorophenyl)-N-(4,4-difluorocyclohexyl)pyrazine-2-carbothioamide::CHEMBL593606

SMILES FC1(F)CCC(CC1)NC(=S)c1cnc(-c2ccc(Cl)cc2)c(n1)-c1ccc(Cl)cc1

InChI Key InChIKey=AGNDHMNUEJDYLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305987   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50305987(5,6-bis(4-chlorophenyl)-N-(4,4-difluorocyclohexyl)...)
Affinity DataIC50:  4.5nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed