BDBM50307943 4-(4-tert-Butylbenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine::CHEMBL597211::US8796293, 56

SMILES: CC(C)(C)c1ccc(CC2(N)CCN(CC2)c2ncnc3[nH]ccc23)cc1

InChI Key: InChIKey=SNNUMARRAFQOGY-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50307943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Human)	BDBM50307943 (US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	7.5	25
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Cytochrome P450 1A2 (Human)	BDBM50307943 (US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50307943 (US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50307943 (US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50307943 (US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50307943 (US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-beta serine/threonine-protein kinase (Human)	BDBM50307943 (US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
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