BDBM50308876 3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin-7-ylcarbamoyl)-benzyl]-benzamide::CHEMBL604087

SMILES: COc1ccc(cc1OC)C(=O)NCc1cccc(c1)C(=O)Nc1ccc2CCNCc2c1

InChI Key: InChIKey=AOTJVGQNGQYEAY-UHFFFAOYSA-N

Data: 19 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50308876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase N2 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 11 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-2 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 26 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent protein kinase 1 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C epsilon type (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division control protein 42 homolog (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C delta type (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50308876 (3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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