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BDBM50308987 (R)-N-(1-(1-(4-(ethylcarbamoyl)phenyl)ethylcarbamoyl)cyclopropyl)pyrimidine-5-carboxamide::CHEMBL591110

SMILES: CCNC(=O)c1ccc(cc1)[C@@H](C)NC(=O)C1(CC1)NC(=O)c1cncnc1

InChI Key: InChIKey=AIKMOFNDAYQBRB-UGPWUYPHNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308987   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))
BDBM50308987
PNG
((R)-N-(1-(1-(4-(ethylcarbamoyl)phenyl)ethylcarbamo...)
Show SMILES CCNC(=O)c1ccc(cc1)[C@@H](C)NC(=O)C1(CC1)NC(=O)c1cncnc1
Show InChI InChI=1/C20H23N5O3/c1-3-23-17(26)15-6-4-14(5-7-15)13(2)24-19(28)20(8-9-20)25-18(27)16-10-21-12-22-11-16/h4-7,10-13H,3,8-9H2,1-2H3,(H,23,26)(H,24,28)(H,25,27)/t13-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Jerini AG

Curated by ChEMBL


Assay Description
Antagonist activity at bradikinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilization


Bioorg Med Chem Lett 20: 1225-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.119
BindingDB Entry DOI: 10.7270/Q27P8ZH1
More data for this
Ligand-Target Pair