BDBM50310487 (R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(1-(4-oxo-3-(4-(2,2,2-trifluoroethoxy)phenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)acetamide::CHEMBL1077831

SMILES: CCS(=O)(=O)CCN([C@H](C)c1nc2ncccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=KKZXIEYKPIMYPS-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50310487   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Human)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 3 (Human)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 3 (Human)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 3 (Human)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Human)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 3 (Rat)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 3 (Mouse)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 3 (Dog)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 3 (Rhesus macaque)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Human)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Human)	BDBM50310487 ((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair