BDBM50311638 2-(6-fluoro-1H-benzo[d]imidazol-1-yl)-9-(tetrahydro-2H-pyran-4-yl)-7H-purin-8(9H)-one::CHEMBL1088424

SMILES Fc1ccc2ncn(-c3ncc4[nH]c(=O)n(C5CCOCC5)c4n3)c2c1

InChI Key InChIKey=CZBNYTJYQPWJEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311638   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311638(2-(6-fluoro-1H-benzo[d]imidazol-1-yl)-9-(tetrahydr...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311638(2-(6-fluoro-1H-benzo[d]imidazol-1-yl)-9-(tetrahydr...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed