BDBM50312906 2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)pyrimidin-5-yl)acetic acid::CHEMBL1088284
SMILES OC(=O)Cc1cnc(nc1-c1cccc(F)c1)C(c1ccc(F)cc1)c1ccc(F)cc1
InChI Key InChIKey=ACFQRXVIUVXHIY-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50312906
Affinity DataIC50: 0.0120nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of rat CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of thromboxane A2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of guinea pig CRTH2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human DP receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of mouse DP receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair