BDBM50314764 CHEMBL1093304::trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)propan-2-yl)acetamide

SMILES: CC(=O)NC(C)(C)[C@@H]1CC2(CCN(CC2)C(=O)[C@@H]2CN(C[C@H]2c2ccc(F)cc2F)C(C)(C)C)c2cc(Cl)c(C)cc12

InChI Key: InChIKey=KMNARKQYUZICHM-UHFFFAOYSA-N

Data: 5 IC50  9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50314764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Rat)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	997	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Melanocortin receptor 3 (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	351	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocyte-stimulating hormone receptor (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mouse)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Rat)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mouse)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Mouse)	BDBM50314764 (trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair