BDBM50314793 (S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosphinic acid::CHEMBL1089515

SMILES N[C@@H](CCP(O)(=O)CCC(O)=O)C(O)=O

InChI Key InChIKey=CIOKCIBFBZYLCA-YFKPBYRVSA-N

Data  18 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50314793   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  5.20E+4nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  3.10E+4nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  7.80E+3nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  6.15E+3nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  7.10E+3nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  3.20E+4nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  3.10E+4nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  8.90E+4nMAssay Description:Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  5.94E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  8.90E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  7.80E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  6.60E+3nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed