BDBM50314794 (3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosphinyl]ethanoic Acid::CHEMBL1089852

SMILES N[C@@H](CCP(O)(=O)CC(O)=O)C(O)=O

InChI Key InChIKey=QNZCMPXFRMGKRU-BYPYZUCNSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50314794   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  5.70E+4nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  910nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  1.31E+5nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed