BDBM50318872 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((pyridin-3-yloxy)methyl)-1H-pyrazol-5-yl)urea::CHEMBL1084269::PF-4618433

SMILES: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cc(COc2cccnc2)n[nH]1)C(C)(C)C

InChI Key: InChIKey=NJARPUHZDSAXPL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50318872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine kinase 2-beta (Human)	BDBM50318872 (1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	637	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Human)	BDBM50318872 (1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	637	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Human)	BDBM50318872 (1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	637	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mouse)	BDBM50318872 (1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Human)	BDBM50318872 (1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair