BDBM50319578 (2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol::CHEMBL1082458

SMILES: CNC[C@@H](O)CCN1c2ccccc2N(c2ccccc2F)S1(=O)=O

InChI Key: InChIKey=PHSDSMUCNUCJGQ-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50319578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair