BDBM50319840 (S)-4-(1-(1-(3-chloro-5-(trifluoromethoxy)benzyl)-1H-indole-7-carboxamido)ethyl)benzoic acid::CHEMBL1084552
SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cc(Cl)cc(OC(F)(F)F)c3)c12)c1ccc(cc1)C(O)=O
InChI Key InChIKey=HQCZRLVYPNLNQN-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50319840
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...More data for this Ligand-Target Pair