BDBM50321746 2-(benzylthio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile::CHEMBL1171912

SMILES N#Cc1c(SCc2ccccc2)nc2CCCCc2c1-c1cccs1

InChI Key InChIKey=CKRPTIHHOUSNTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321746   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321746(2-(benzylthio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydr...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant histidine-tagged ALK (103-1459) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321746(2-(benzylthio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydr...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of human recombinant histidine-tagged ABL (230-517) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321746(2-(benzylthio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydr...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant histidine-tagged RET (700-1020) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed