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BDBM50324161 (+/-)-4-[5-(4-Fluorophenyl)-1-(4-nitrophenyl)-4,5-dihydro-1Hpyrazol-3-yl]phenol::CHEMBL1215689

SMILES: Oc1ccc(cc1)C1=NN(C(C1)c1ccc(F)cc1)c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=HPYCSMRZVJTSRQ-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324161   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM50324161
PNG
((+/-)-4-[5-(4-Fluorophenyl)-1-(4-nitrophenyl)-4,5-...)
Show SMILES Oc1ccc(cc1)C1=NN(C(C1)c1ccc(F)cc1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1/C21H16FN3O3/c22-16-5-1-15(2-6-16)21-13-20(14-3-11-19(26)12-4-14)23-24(21)17-7-9-18(10-8-17)25(27)28/h1-12,21,26H,13H2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 460n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assay


J Med Chem 53: 5979-6002 (2010)


Article DOI: 10.1021/jm100505n
BindingDB Entry DOI: 10.7270/Q2T43V2T
More data for this
Ligand-Target Pair