BDBM50324592 (R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-pyrazol-4-yl)phenyl)-2-ethyl-1,2,3,4-tetra-hydroisoquinoline-3-carboxamide::CHEMBL1215526

SMILES: CCN1Cc2ccccc2C[C@@H]1C(=O)Nc1cc(F)c(cc1OCCN(C)C)-c1cn[nH]c1

InChI Key: InChIKey=ZNDQOACBIHODQO-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Human)	BDBM50324592 ((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM50324592 ((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK alpha (Human)	BDBM50324592 ((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM50324592 ((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50324592 ((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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