BDBM50325913 2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimidin-4(3H)-one::CHEMBL1224070

SMILES Clc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1

InChI Key InChIKey=JAETYFQMGNCXCJ-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50325913   

TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325913(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Affinity DataIC50:  15nMAssay Description:Displacement of radioligand from human GPR109AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325913(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at rat GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325913(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of radioligand from rat GPR109AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325913(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325913(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Affinity DataIC50:  3.30E+4nMAssay Description:Displacement of radioligand from human GPR109BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed