BDBM50325924 2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrimidin-4(3H)-one::CHEMBL1224219

SMILES Clc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1

InChI Key InChIKey=HEKFYWONLKTJOD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325924   

TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325924(2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataIC50:  50nMAssay Description:Displacement of radioligand from human GPR109AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325924(2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataIC50:  640nMAssay Description:Displacement of radioligand from rat GPR109AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325924(2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataEC50:  340nMAssay Description:Agonist activity at human GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50325924(2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at rat GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed