BDBM50298223 CGP-57380::CHEMBL1240885::CHEMBL576817::N-(4-fluorophenyl)-3H-pyrazolo[3,4-d]pyrimidine-3,4-diamine

SMILES: Nc1ncnc2n[nH]c(Nc3ccc(F)cc3)c12

InChI Key: InChIKey=UQPMANVRZYYQMD-UHFFFAOYSA-N

Data: 2 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50298223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform delta (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase BRSK2 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity tyrosine-phosphorylation-regulated kinase 3 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase LCK (Mouse)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM50298223 (CHEMBL576817 | CHEMBL1240885 | CGP-57380 | N-(4-fl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair