BDBM50328156 6-(1-isobutyl-1H-pyrazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)pyrimidin-4-amine::CHEMBL1257658::US9670214, TABLE 16.45

SMILES: CC(C)Cn1cc(cn1)-c1cc(Nc2ccc(OC(F)(F)F)cc2)ncn1

InChI Key: InChIKey=VRLVMMQZIBLEME-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-specific protein-tyrosine kinase (Human)	BDBM50328156 (6-(1-isobutyl-1H-pyrazol-4-yl)-N-(4-(trifluorometh...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Non-specific protein-tyrosine kinase [T818I] (Human)	BDBM50328156 (6-(1-isobutyl-1H-pyrazol-4-yl)-N-(4-(trifluorometh...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50328156 (6-(1-isobutyl-1H-pyrazol-4-yl)-N-(4-(trifluorometh...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair