BDBM50328189 (4-(pyrrolidin-1-yl)piperazin-1-yl)(4-(4-(trifluoromethoxy)phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanone::CHEMBL1257541::US9670214, TABLE 13.12

SMILES: FC(F)(F)Oc1ccc(Nc2ncnc3sc(cc23)C(=O)N2CCN(CC2)N2CCCC2)cc1

InChI Key: InChIKey=WQHXIMCGFHBRFN-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-specific protein-tyrosine kinase (Human)	BDBM50328189 ((4-(pyrrolidin-1-yl)piperazin-1-yl)(4-(4-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-specific protein-tyrosine kinase [T818I] (Human)	BDBM50328189 ((4-(pyrrolidin-1-yl)piperazin-1-yl)(4-(4-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50328189 ((4-(pyrrolidin-1-yl)piperazin-1-yl)(4-(4-(trifluor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair