BDBM50328197 3-(4-(4-(trifluoromethoxy)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propanamide::CHEMBL1258009::US9670214, TABLE 12.7

SMILES: NC(=O)CCn1ccc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc12

InChI Key: InChIKey=XLVMADINVYYTKE-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-specific protein-tyrosine kinase (Human)	BDBM50328197 (3-(4-(4-(trifluoromethoxy)phenylamino)-7H-pyrrolo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Non-specific protein-tyrosine kinase [T818I] (Human)	BDBM50328197 (3-(4-(4-(trifluoromethoxy)phenylamino)-7H-pyrrolo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.42E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50328197 (3-(4-(4-(trifluoromethoxy)phenylamino)-7H-pyrrolo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair