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BDBM50331194 4-(4-methoxyphenyl)-1-(9-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-7-yl)pyridin-2(1H)-one::CHEMBL1289723

SMILES: COc1ccc(cc1)-c1ccn(-c2ccc3c4CCNCc4n(C)c3c2)c(=O)c1

InChI Key: InChIKey=AHDBPAJCLCZWMX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331194   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50331194
PNG
(4-(4-methoxyphenyl)-1-(9-methyl-2,3,4,9-tetrahydro...)
Show SMILES COc1ccc(cc1)-c1ccn(-c2ccc3c4CCNCc4n(C)c3c2)c(=O)c1
Show InChI InChI=1S/C24H23N3O2/c1-26-22-14-18(5-8-20(22)21-9-11-25-15-23(21)26)27-12-10-17(13-24(27)28)16-3-6-19(29-2)7-4-16/h3-8,10,12-14,25H,9,11,15H2,1-2H3
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Article
PubMed
14n/an/an/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells


Bioorg Med Chem Lett 20: 7024-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.122
BindingDB Entry DOI: 10.7270/Q2XP7569
More data for this
Ligand-Target Pair