BDBM50331277 3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridine::CHEMBL1288582

SMILES: COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12

InChI Key: InChIKey=PRASIGARSOSUQT-UHFFFAOYSA-N

Data: 32 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50331277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Wee1-like protein kinase (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase TTK (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK4 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C theta type (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lymphokine-activated killer T-cell-originated protein kinase (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 2 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Nek2 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase II subunit alpha (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK beta (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Death-associated protein kinase 1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
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