BDBM50334484 4-(1-(3,5-bis(4-(trifluoromethoxy)phenyl)-1H-pyrazol-1-yl)ethyl)-N-(2H-tetrazol-5-yl)benzamide::CHEMBL1644188

SMILES CC(c1ccc(cc1)C(=O)Nc1nnn[nH]1)n1nc(cc1-c1ccc(OC(F)(F)F)cc1)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=UCXDATDHRBYGIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334484   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334484(4-(1-(3,5-bis(4-(trifluoromethoxy)phenyl)-1H-pyraz...)
Affinity DataIC50:  130nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334484(4-(1-(3,5-bis(4-(trifluoromethoxy)phenyl)-1H-pyraz...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at human GIPR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334484(4-(1-(3,5-bis(4-(trifluoromethoxy)phenyl)-1H-pyraz...)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed