BDBM50336465 (3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10,11,12-octahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione::CHEMBL1668413

SMILES COc1cc(O)c2c(CCCCCC(=O)C[C@H](Cl)C[C@H](C)OC2=O)c1

InChI Key InChIKey=GLRILJLJSBHYAR-GXTWGEPZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50336465   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University Of Ireland

Curated by ChEMBL
LigandPNGBDBM50336465((3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University Of Ireland

Curated by ChEMBL
LigandPNGBDBM50336465((3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University Of Ireland

Curated by ChEMBL
LigandPNGBDBM50336465((3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,...)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University Of Ireland

Curated by ChEMBL
LigandPNGBDBM50336465((3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University Of Ireland

Curated by ChEMBL
LigandPNGBDBM50336465((3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed