BDBM50336977 CHEMBL1672627::N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide

SMILES: Fc1cnccc1-c1ncc(NC(=O)C2CC2)nc1-c1cccnc1

InChI Key: InChIKey=XUYURJQIMYCWBB-UHFFFAOYSA-N

Data: 4 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50336977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2b (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2b (Mouse)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2b (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50336977 (N-[5-(3-Fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair