BDBM50337935 5-(2-fluoro-4-iodophenylamino)-3,8-dimethylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione::CHEMBL1684060::US8470837, 1

SMILES: Cn1cnc2n(C)c(=O)cc(Nc3ccc(I)cc3F)c2c1=O

InChI Key: InChIKey=KZRPLGCWNHYBDB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 [2-31,52-393,S218E,S222D] (Human)	BDBM50337935 (US8470837, 1 | CHEMBL1684060 | 5-(2-fluoro-4-iodop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>16	n/a	n/a	n/a	n/a	7.3	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50337935 (US8470837, 1 | CHEMBL1684060 | 5-(2-fluoro-4-iodop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair