BDBM50337958 CHEMBL1684242::N-cyclobutyl-6-((3-fluorophenyl)ethynyl)nicotinamide
SMILES Fc1cccc(c1)C#Cc1ccc(cn1)C(=O)NC1CCC1
InChI Key InChIKey=NEMHWVUKNWAKTM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50337958
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: 195nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in human HEK293 cells after 1 hr by scintillation counterMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center
Curated by ChEMBL
Vanderbilt Medical Center
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair