BDBM50339375 (+/-)-2-(4-Bromobenzyl)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)isoindolin-1-one::CHEMBL1688280::US8618158, NU8417

SMILES: OCC1(COC2(N(Cc3ccc(Br)cc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=YMEMJYRVAROGJU-UHFFFAOYSA-N

Data: 2 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM50339375 (US8618158, NU8417 | CHEMBL1688280 | (+/-)-2-(4-Bro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM50339375 (US8618158, NU8417 | CHEMBL1688280 | (+/-)-2-(4-Bro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair