BDBM50339636 1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea Hydrochloride::CHEMBL1688889

SMILES: CC(C)Oc1cccc(NC(=O)NC(=O)c2cc3c(C)nn(C)c3nc2N(C)CCN(C)C)c1

InChI Key: InChIKey=MFORNGKVWCJAME-UHFFFAOYSA-N

Data: 16 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50339636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 2 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 2 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 1 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 5 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 5 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 1 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 3 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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C-C chemokine receptor type 5 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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C-C chemokine receptor type 3 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 4 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 1 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 2 (Human)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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C-C chemokine receptor type 2 (Mouse)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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C-C chemokine receptor type 2 (Rat)	BDBM50339636 (1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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