BDBM50339636 1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea Hydrochloride::CHEMBL1688889
SMILES CC(C)Oc1cccc(NC(=O)NC(=O)c2cc3c(C)nn(C)c3nc2N(C)CCN(C)C)c1
InChI Key InChIKey=MFORNGKVWCJAME-UHFFFAOYSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50339636
Affinity DataIC50: 80nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CCR2 in rat spleen cells assessed as inhibition of CCL2-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at CCR2 in human PBMC cells assessed as inhibition of CCL2-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR1 in human PBMC cells assessed as inhibition of CCL3-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR5 in human PBMC cells assessed as inhibition of CCL3-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Antagonist activity at CCR5 in human PBMC cells assessed as inhibition of CCL4-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR1 in human PBMC cells assessed as inhibition of CCL5-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR3 in human PBMC cells assessed as inhibition of CCL5-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR5 in human PBMC cells assessed as inhibition of CCL5-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR1 in eosinophil cells assessed as inhibition of CCL11-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR3 in eosinophil cells assessed as inhibition of CCL11-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR4 in transfected in THP-1 cells assessed as inhibition of CCL17-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CXCR1 in human PMN cells assessed as inhibition of CXCL8-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CXCR2 in human PMN cells assessed as inhibition of CXCL8-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at CCR2 in mouse spleen cells assessed as inhibition of CCL2-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis after 2 hrs trans-well migration assayMore data for this Ligand-Target Pair