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BDBM50340357 2-(4-biphenyl)-1-{3-[4-(3-acetylaminophenyl)piperidin-1-yl]propyl}-1H-benzimidazole::CHEMBL1761114

SMILES: CC(=O)Nc1cccc(c1)C1CCN(CCCn2c(nc3ccccc23)-c2ccc(cc2)-c2ccccc2)CC1

InChI Key: InChIKey=FFYYMPKYCYWKII-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50340357
PNG
(2-(4-biphenyl)-1-{3-[4-(3-acetylaminophenyl)piperi...)
Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCn2c(nc3ccccc23)-c2ccc(cc2)-c2ccccc2)CC1
Show InChI InChI=1S/C35H36N4O/c1-26(40)36-32-12-7-11-31(25-32)29-19-23-38(24-20-29)21-8-22-39-34-14-6-5-13-33(34)37-35(39)30-17-15-28(16-18-30)27-9-3-2-4-10-27/h2-7,9-18,25,29H,8,19-24H2,1H3,(H,36,40)
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Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of Eu-labeled MCH from human MCH-R1 expressed in CHO by time-resolved fluorometric assay


Bioorg Med Chem Lett 21: 2309-12 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.099
BindingDB Entry DOI: 10.7270/Q20002DT
More data for this
Ligand-Target Pair