BDBM50341378 CHEBI:9921::Valerenic Acid

SMILES [H][C@]12CCC(C)=C1[C@@H](CC[C@H]2C)\C=C(/C)C(O)=O

InChI Key InChIKey=FEBNTWHYQKGEIQ-SUKRRCERSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50341378   

TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  5.20E+3nMAssay Description:Transactivation of human Gal4-fused RXRbeta LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  4.30E+4nMAssay Description:Transactivation of human Gal4-fused RXRgamma LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  2.70E+4nMAssay Description:Transactivation of human Gal4-fused RXRalpha LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  4.30E+4nMAssay Description:Antagonist activity at human NK1 receptor expressed in CHO cells assessed as inhibition of SP-induced intracellular Ca2+ increase by Fura-2 assayMore data for this Ligand-Target Pair
In DepthDetails
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  1.26E+4nMAssay Description:Positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-indu...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  2.70E+4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea pig ileum muscleMore data for this Ligand-Target Pair
In DepthDetails
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  5.20E+3nMAssay Description:Antagonist activity at human NK1 receptor expressed in CHO cells assessed as inhibition of SP-induced intracellular Ca2+ increase by Fura-2 assayMore data for this Ligand-Target Pair
In DepthDetails
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  1.90E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed