BDBM50341443 (Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetamide::CHEMBL1766988

SMILES Clc1cccc(NC(=O)COc2ccc(\C=C3/SC(=O)NC3=O)cc2)c1

InChI Key InChIKey=UENKSVGEBXJETK-NVNXTCNLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341443   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341443((Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin...)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of iNOS in LPS-stimulated mouse RAW 264.7 cells after 2 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341443((Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin...)
Affinity DataIC50:  4.16E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW 264.7 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341443((Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin...)
Affinity DataIC50:  8.66E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells treated 2 hrs before LPS challenge measured after 18 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed