BDBM50342715 3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]isoquinolin-1(2H)-one::CHEMBL1771109

SMILES: COc1ccccc1N1CCN(CCCCN2CCc3cc(ccc3C2=O)-c2ccco2)CC1

InChI Key: InChIKey=NEDWSVCVHMJKSZ-UHFFFAOYSA-N

Data: 5 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Human)	BDBM50342715 (3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50342715 (3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50342715 (3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50342715 (3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Pig)	BDBM50342715 (3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Pig)	BDBM50342715 (3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair