BDBM50342893 6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-2-ylmethyl)quinazolin-4-amine::CHEMBL1725513

SMILES C(Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1)c1ccco1

InChI Key InChIKey=OHNZJKJYATYGCV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342893   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342893(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-2-ylmethyl)q...)
Affinity DataIC50:  534nMAssay Description:Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342893(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-2-ylmethyl)q...)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342893(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-2-ylmethyl)q...)
Affinity DataIC50:  192nMAssay Description:Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342893(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-2-ylmethyl)q...)
Affinity DataIC50:  79nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342893(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-2-ylmethyl)q...)
Affinity DataIC50:  84nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342893(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-2-ylmethyl)q...)
Affinity DataIC50:  301nMAssay Description:Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed