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BDBM50343460 CHEMBL1773288::tert-butyl 4-(3-methyl-1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate

SMILES: Cc1nn(-c2ccc(cc2)S(C)(=O)=O)c2ncnc(OC3CCN(CC3)C(=O)OC(C)(C)C)c12

InChI Key: InChIKey=AHNQYAZOPGIERI-UHFFFAOYSA-N

Data: 2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343460   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucose-dependent insulinotropic receptor


(Rattus norvegicus)
BDBM50343460
PNG
(CHEMBL1773288 | tert-butyl 4-(3-methyl-1-(4-(methy...)
Show SMILES Cc1nn(-c2ccc(cc2)S(C)(=O)=O)c2ncnc(OC3CCN(CC3)C(=O)OC(C)(C)C)c12
Show InChI InChI=1S/C23H29N5O5S/c1-15-19-20(28(26-15)16-6-8-18(9-7-16)34(5,30)31)24-14-25-21(19)32-17-10-12-27(13-11-17)22(29)33-23(2,3)4/h6-9,14,17H,10-13H2,1-5H3
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PC sid
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Article
PubMed
n/an/an/an/a 42n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at rat GPR119 by melanophore assay


Bioorg Med Chem Lett 21: 3134-41 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.007
BindingDB Entry DOI: 10.7270/Q24T6JQF
More data for this
Ligand-Target Pair
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50343460
PNG
(CHEMBL1773288 | tert-butyl 4-(3-methyl-1-(4-(methy...)
Show SMILES Cc1nn(-c2ccc(cc2)S(C)(=O)=O)c2ncnc(OC3CCN(CC3)C(=O)OC(C)(C)C)c12
Show InChI InChI=1S/C23H29N5O5S/c1-15-19-20(28(26-15)16-6-8-18(9-7-16)34(5,30)31)24-14-25-21(19)32-17-10-12-27(13-11-17)22(29)33-23(2,3)4/h6-9,14,17H,10-13H2,1-5H3
Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 15n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 by melanophore assay


Bioorg Med Chem Lett 21: 3134-41 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.007
BindingDB Entry DOI: 10.7270/Q24T6JQF
More data for this
Ligand-Target Pair