BDBM50343530 5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(methyl)amino)quinoline-2-carboxylic acid::CHEMBL1774309

SMILES: COc1ccc(Sc2cccc(CN(C)c3cc(nc4cc(Cl)cc(Cl)c34)C(O)=O)c2)cc1

InChI Key: InChIKey=FUUIYLWURGZBJB-UHFFFAOYSA-N

Data: 1 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50343530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E synthase (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 18 (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 5 (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 9 (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein phosphatase 3 (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein phosphatase Slingshot homolog 2 (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Protein phosphatase 1A (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein phosphatase 1G (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5A (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 22 (Human)	BDBM50343530 (5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...) Show SMILES Show InChI	GoogleScholar	UniChem		5.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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