BDBM50343725 (S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile::CHEMBL1774055

SMILES: C[C@H](Nc1nc(Nc2cc(C)n[nH]2)c(F)cc1C#N)c1ccc(F)cc1

InChI Key: InChIKey=SUNXHXDJOIXABJ-UHFFFAOYSA-N

Data: 1 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50343725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 1 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
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LIM domain kinase 2 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
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LIM domain kinase 1 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
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LIM domain kinase 2 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
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LIM domain kinase 1 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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LIM domain kinase 2 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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LIM domain kinase 1/2 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) Show SMILES Show InChI	GoogleScholar	UniChem		0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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