BDBM50345437 6-ethyl-N-(4-isopropylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::CHEMBL1784714::US9238653, Table 5, Compound 8

SMILES: CCc1c(C)nc2ncnn2c1Nc1ccc(cc1)C(C)C

InChI Key: InChIKey=HSKDDEMAAZUZGH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM50345437 (6-ethyl-N-(4-isopropylphenyl)-5-methyl-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (malaria parasite P. falciparum)	BDBM50345437 (6-ethyl-N-(4-isopropylphenyl)-5-methyl-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50345437 (6-ethyl-N-(4-isopropylphenyl)-5-methyl-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair