BDBM50345440 CHEMBL1784717::N-(3-fluoro-4-methylphenyl)-6,7-dihydro-5H-cyclopenta[d][1,2,4]triazolo[1,5-a]pyrimidin-8-amine::US9238653, Table 5, Compound 37

SMILES: Cc1ccc(Nc2c3CCCc3nc3ncnn23)cc1F

InChI Key: InChIKey=NBQRWNDOUQGFIX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345440   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM50345440 (N-(3-fluoro-4-methylphenyl)-6,7-dihydro-5H-cyclope...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (malaria parasite P. falciparum)	BDBM50345440 (N-(3-fluoro-4-methylphenyl)-6,7-dihydro-5H-cyclope...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50345440 (N-(3-fluoro-4-methylphenyl)-6,7-dihydro-5H-cyclope...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair